Bhattacharya, M. K. ; Nair, G. B. ; Sen, D. ; Paul, M. ; Debnath, A. ; Nag, A. ; Dutta, D. ; Dutta, P. ; Pal, S. C. ; Bhattacharya, S. K. (1992) Efficacy of norfloxacin for shigellosis: a double-blind randomised clinical trial Journal Diarrhoeal Disease Research, 10 (3). pp. 146-150. ISSN 0253-8768
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Abstract
In a double-blind, randomised, clinical trial on 122 adults with acute Shigella dysentery, 60 patients were treated with norfloxacin and 62 with nalidixic acid. Of these, 32 patients in the norfloxacin group and 28 patients in the nalidixic acid group had Shigella in their stool. Patients of the two treatment groups were clinically comparable on admission. No significant differences in clinical responses were observed in the two groups among the Shigella-positive cases, Shigella-negative cases and among the total cases. All isolates of Shigella were susceptible to norfloxacin, whereas 13.8% of the strains were resistant to nalidixic acid.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to International Centre for Diarrhoeal Disease Research, Bangladesh. |
| ID Code: | 80814 |
| Deposited On: | 02 Feb 2012 03:58 |
| Last Modified: | 02 Feb 2012 03:58 |
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