Emergence of tetracycline resistance due to a multiple drug resistance plasmid in Vibrio cholerae O139

Yamamoto, Tatsuo ; Balakrish Nair, G. ; Takeda, Yoshifumi (1995) Emergence of tetracycline resistance due to a multiple drug resistance plasmid in Vibrio cholerae O139 FEMS Immunology and Medical Microbiology, 11 (2). pp. 131-136. ISSN 1574-695X

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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1574-...

Related URL: http://dx.doi.org/10.1111/j.1574-695X.1995.tb00099.x

Abstract

Abstract Of the 173 clinical strains of Vibrio cholerae O139 isolated from India, Bangladesh, and Thailand tested, six strains from India were resistant to tetracycline, ampicillin, chloramphenicol, kanamycin, and gentamicin. These six strains harbored a self-transmissible plasmid that mediated resistance to tetracycline, ampicillin, chloramphenicol, kanamycin, gentamicin, sulfamethoxazole, trimethoprim, and O/129. The multiple drug resistance plasmids were 200 kb in size and belonged to the incompatibility group C. Although a majority of the O139 strains (94.8%) were highly resistant to streptomycin, sulfamethoxazole, trimethoprim, and O/129, the tetracycline-susceptible strains so far tested were plasmid-negative. The data suggest the existence of two distinct multiple antimicrobial agent resistance (MAR) patterns in V. cholerae O139.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
Keywords:Vibrio Cholerae O139; Tetracycline Resistance; Multiple Drug Resistance; Plasmid
ID Code:80775
Deposited On:02 Feb 2012 04:06
Last Modified:02 Feb 2012 04:06

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