Reactivity of the ω-halogen atom in p-alkoxybenzyl halides: preparation of phenylacetic acids

Naik, R. G. ; Wheeler , T. S. (1938) Reactivity of the ω-halogen atom in p-alkoxybenzyl halides: preparation of phenylacetic acids Journal of the Chemical Society . pp. 1780-1783. ISSN 0368-1769

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Official URL: http://pubs.rsc.org/en/Content/ArticleLanding/1938...

Related URL: http://dx.doi.org/10.1039/JR9380001780

Abstract

p-Alkoxybenzyl acohols (obtained from the aldehydes by the Cannizzaro reaction) give with halogen acids the corresponding chlorides and bromides, and these, with potassium cyanide, yield p-alkoxyphenylacetonitriles and thence p-alkoxyphyl-acetic acids. The ω - halogen atom in the p- alkoxybenzyl halides readil aloy reacts with alcohols.

Item Type:Article
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