Multilocus variable-number tandem repeat analysis of Vibrio cholerae O1 El Tor strains harbouring classical toxin B

Choi, Seon Young ; Lee, Je Hee ; Jeon, Yoon-Seong ; Lee, Hye Ri ; Kim, Eun Jin ; Ansaruzzaman, M. ; Bhuiyan, Nurul A. ; Endtz, Hubert P. ; Niyogi, S. K. ; Sarkar, B. L. ; Balakrish Nair, G. ; Nguyen, Binh Minh ; Hien, Nguyen Tran ; Czerkinsky, Cecil ; Clemens, John D. ; Chun, Jongsik ; Kim, Dong Wook (2010) Multilocus variable-number tandem repeat analysis of Vibrio cholerae O1 El Tor strains harbouring classical toxin B Journal of Medical Microbiology, 59 (7). pp. 763-769. ISSN 0022-2615

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Official URL: http://jmm.sgmjournals.org/content/59/7/763.abstra...

Related URL: http://dx.doi.org/10.1099/jmm.0.017939-0

Abstract

Atypical Vibrio cholerae O1 strains - hybrid strains (strains that cannot be classified either as El Tor or classical biotype) and altered strains (El Tor biotype strains that produce classical cholera toxin) - are currently prevalent in Asia and Africa. A total of 74 hybrid and altered strains that harboured classical cholera toxin were investigated by multilocus variable-number tandem repeat analysis (MLVA). The results showed that the hybrid/altered strains could be categorized into three groups and that they were distant from the El Tor strain responsible for the seventh cholera pandemic. Hybrid/altered strains with a tandem repeat of the classical CTX prophage on the small chromosome were divided into two MLVA groups (group I: Mozambique/Bangladesh group; group III: Vietnam group), and altered strains with the RS1-CTX prophage containing the El Tor type rstR and classical ctxB on the large chromosome were placed in two MLVA groups (group II: India/Bangladesh group; group III: India/Vietnam group).

Item Type:Article
Source:Copyright of this article belongs to Society for General Microbiology.
Keywords:CT; Cholera Toxin MLVA; Multilocus Variable-number Tandem Repeat Analysis
ID Code:80555
Deposited On:01 Feb 2012 13:07
Last Modified:01 Feb 2012 13:07

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