Serjeantson, S. W. ; Ranford, P. R. ; Kirk, R. L. ; Kohonen-Corish, M. R. ; Mohan, V. ; Ramachandran, A. ; Snehalatha, C. ; Viswanathan, M. (1987) HLA-DR and DQ-DNA genotyping in insulin dependent diabetic patients in South India Disease Markers, 5 (2). pp. 101-108. ISSN 0278-0240
Full text not available from this repository.
Official URL: http://iospress.metapress.com/content/0278-0240/?s...
Abstract
Restriction fragment length polymorphisms (RFLPs) of the HLA-DR #946;, -DQ α, -DQ β , and -DX α genes have been examined in South Indian diabetic patients and controls. The DR. DQ linkage arrangements in South Indians were shown to be different for DR2, DR4, and DRw6 from those commonly seen in Europeans, so that localization of the primary disease-promoting gene in IDDM could be attempted. This study clearly implicates at least one DQ β allele in the pathogenesis of IDDM.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to IOS Press. |
| ID Code: | 80515 |
| Deposited On: | 01 Feb 2012 09:33 |
| Last Modified: | 01 Feb 2012 09:33 |
Repository Staff Only: item control page
