Transition-metal saccharide chemistry and biology: synthesis, characterisation, redox behaviour, biointeraction and data correlations of dinuclear chromium(III) complexes

Abstract

A series of dinuclear chromium(III) complexes has been synthesised by reduction of chromate by a variety of saccharides and related compounds. The complexes have been characterised by various analytical (elemental and ICP-AES analysis, TLC, HPLC) and spectroscopic (UV/VIS, FTIR, EPR, ¹H and ¹³C NMR) methods. Antiferromagnetic interactions between the two Cr^III centres have been established by magnetic susceptibility measurements and the hydrolytic stability and redox behaviour of the complexes have been established by extensive electrochemical studies which gave several correlations. The interaction of some of the complexes with DNA has been studied by gel electrophoresis.