Metal-saccharide chemistry and biology: saccharide complexes of zinc and their effect on metallothionein synthesis in mice

Bandwar, Rajiv P. ; Giralt, Mercedes ; Hidalgo, Juan ; Rao, Chebrolu P. (1996) Metal-saccharide chemistry and biology: saccharide complexes of zinc and their effect on metallothionein synthesis in mice Carbohydrate Research, 284 (1). pp. 73-84. ISSN 0008-6215

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Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0008-6215(96)00009-2

Abstract

Monosaccharide (D-Fru, D-Gal, D-Glc, D-Xyl, and D-Rib) and disaccharide (Mal) complexes of Zn2+ were synthesised using different precursors and isolated in the solid state. These were found to be anionic with a Zn-to-saccharide ratio of 1:1 and 2:1 for monosaccharide and disaccharide complexes, respectively. Electrochemical behaviour in aqueous solution was studied by extensive cyclic voltammetric studies in the pH range 3.7-10.3. The effect of subcutaneously injected Zn-D-Fru, Zn-D-Gal and Zn-D-Glc complexes on the metallothionein synthesis in mice was found to be significant in the liver, but not in the brain.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Complex; Metal-saccharide; Zinc-saccharide Complex; Metallothionein
ID Code:79134
Deposited On:24 Jan 2012 15:20
Last Modified:19 Apr 2012 05:43

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