Synthesis of chiral α-amino acids

Chakraborty, Tushar K. ; Ghosh, Animesh (2002) Synthesis of chiral α-amino acids Tetrahedron Letters, 43 . pp. 9691-9693. ISSN 0040-4039

Full text not available from this repository.

Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(02)02433-4

Abstract

A novel method for the synthesis of chiral α-amino acids has been developed where the acid functionality was constructed by oxidizing a hydroxymethyl group introduced by Evans' method in the α-position of an appropriate acid substrate and the amino part came from the amide of the original carboxyl group following a modified Hofmann rearrangement reaction.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:α-amino Acids; Hofmann Rearrangement; Oxazolidinone; Evans' Reaction
ID Code:78259
Deposited On:18 Jan 2012 12:14
Last Modified:18 Jan 2012 12:14

Repository Staff Only: item control page