Characterization of a polypeptide from human seminal plasma with inhibin (inhibition of FSH secretion)-like activity

Sheth, Anil R. ; Arabatti, Nandita ; Carlquist, Mats ; Jörnvall, Hans (1984) Characterization of a polypeptide from human seminal plasma with inhibin (inhibition of FSH secretion)-like activity FEBS Letters, 165 (1). pp. 11-15. ISSN 0014-5793

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Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0014-5793(84)80004-6

Abstract

A polypeptide in preparations of 'large' form (Mr ~ 14000) material with inhibin-like activity (inhibiting FSH secretion) has been isolated from human seminal plasma. Its amino acid composition, cleavage pattern with CNBr, N-terminal sequence, and properties on reverse-phase high-performance liquid chromatography establish this inhibin-like preparation to be homogeneous. The polypeptide contains close to 130 residues, has a free N-terminal serine residue, a methionine residue in position 19, and a dibasic structure (Arg-Lys) in positions 16-17

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Seminal Plasma; Feed-back control; Amino Acid Sequence; High Performance Liquid Chromatography
ID Code:78214
Deposited On:18 Jan 2012 08:13
Last Modified:18 Jan 2012 08:13

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