Suppression of lipid peroxidation in human spermatozoa by prostatic inhibin

Bandivdekar, A. H. ; Devasagayam, T. P. A. ; Pradhan, D. S. ; Joseph, D. R. ; Hurkadli, K. S. ; Sheth, A. R. (1989) Suppression of lipid peroxidation in human spermatozoa by prostatic inhibin Systems Biology in Reproductive Medicine, 22 (3). pp. 217-221. ISSN 1939-6368

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Official URL: http://informahealthcare.com/doi/abs/10.3109/01485...

Related URL: http://dx.doi.org/10.3109/01485018908986775

Abstract

Loss of sperm motility owing to the production of hydrogen peroxide by lipid peroxidation is regulated by yet unidentified prostatic factor(s). Inhibinlike peptide (HSPI) of prostatic origin isolated from human seminal plasma and having a molecular weight of about 10,400 daltons was studied for its effect on ascorbate-induced lipid peroxidation in human spermatozoa. Dose-related suppression of lipid peroxidation occurred at a dose level of 0.25, 0.5, and 1.0 μg. HSPI may be one of the factors involved in the regulation of lipid peroxidation and therefore sperm motility.

Item Type:Article
Source:Copyright of this article belongs to Informa plc.
Keywords:Inhibin; Prostate; Sperm; Lipid
ID Code:78083
Deposited On:17 Jan 2012 09:41
Last Modified:17 Jan 2012 09:41

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