Chauhan, Vir S. ; Ratcliffe, Steven J. ; Young, Geoffrey T. (1980) Hydroxy-and amino-protection based on the 4-dimethylcarbamoylbenzyl group International Journal of Peptide and Protein Research, 15 (2). pp. 96-101. ISSN 0367-8377
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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1399-...
Related URL: http://dx.doi.org/10.1111/j.1399-3011.1980.tb02555.x
Abstract
O-4-Dimethylcarbamoylbenzyl-L-tyrosine, N (e)-4-dimethylcarbamoylbenzyl-oxycarbonyl-L-lysine, and simple derivatives, have been prepared. The protecting groups are markedly more stable to trifluoroacetic acid than are the unsubstituted benzyl analogues. N-t-Butoxycarbonyl-O-4-dimethylcarbamoylbenzyl-L-serine (cyclohexylammonium salt) is also described.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Munksgaard International Publishers. |
| Keywords: | Amino-protection; 4-dimethylcarbamoylbenzyl Alcohol; 4-dimethylcarbamoylbenzyl Bromide; Hydroxy-protection; Lysine; Peptide Synthesis; Serine; Tyrosine |
| ID Code: | 77503 |
| Deposited On: | 12 Jan 2012 14:36 |
| Last Modified: | 12 Jan 2012 14:36 |
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