Palekar, Malini S. ; Sirsat, Satyavati M. (1975) Lanthanum staining of cell surface and junctional complexes in normal and malignant human oral mucosa Journal of Oral Pathology & Medicine, 4 (5). pp. 231-243. ISSN 0904-2512
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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1600-...
Related URL: http://dx.doi.org/10.1111/j.1600-0714.1975.tb01863.x
Abstract
Biopsies from normal and malignant human oral epithelium were studied electron histochemically using lanthanum nitrate for a selective demonstration of junctional complexes at the plasma membrane of adjacent cells. The heavy metal complex was found to settle irregularly, sometimes in intimate proximity to the epithelial cell, in areas corresponding to the glycocalyx, gap junctions, desmosomes and nonspecific contact areas. Tight junctions were rarely seen. The lack of these morphological adhesive areas, the desmosomal detachment seen between cancer cells and the increased lanthanum-positive cell surface may be possible factors responsible for the dissociation of oral malignant cells.
Item Type: | Article |
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Source: | Copyright of this article belongs to John Wiley and Sons. |
ID Code: | 77383 |
Deposited On: | 12 Jan 2012 08:00 |
Last Modified: | 12 Jan 2012 08:00 |
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