Venkateswara, R. R. ; Dipak, D. ; Banning, J. W. ; Vaidyanathan, C. S. (1990) Cryptosin induces backbone structural changes in cardiac Na+ and K+ dependent adenosinetriphosphatase Biochemistry International, 22 (2). pp. 287-294. ISSN 0158-5231
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Official URL: http://www.venkatrao.net/files/2290097.pdf
Abstract
Cryptosin, a new cardenolide, was found to preferentially bind to Na,K-ATPase enzyme (7), which is believed to be the ouabain binding site on cardiac sarcolemmal membrane. CD spectral studies revealed that cryptosin, in the presence of Na+ and Mg++ ions, bind to Na,K-ATPase and induce a dose-dependent change in the backbone structure of cardiac Na,K-ATPase.
Item Type: | Article |
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Source: | Copyright of this article belongs to Academic Press Aust. |
ID Code: | 76961 |
Deposited On: | 09 Jan 2012 03:55 |
Last Modified: | 09 Jan 2012 03:55 |
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