Dutta, M. ; Bandyopadhyay, R. ; Ghosh, C. ; Basu, M. K. (1990) Fluidity-dependent Mg2+-ATPase activity in membranes from Leishmania donovani promastigotes Biochemical Journal, 265 . pp. 923-926. ISSN 0264-6021
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Official URL: http://www.biochemj.org/bj/265/bj2650923.htm
Abstract
The state of the lipid phase of the membrane plays a key role in the exposure of various receptors, antigens and enzymes on the membrane surface. The fluidity of membranes of Leishmania donovani promastigotes was monitored by two independent methods, i.e. influx of sterol from liposomes and removal of phospholipids by treatment with phospholipase C. The altered sterol/phospholipid ratio, in both cases, provided evidence that the activity of the functionally important membrane-bound enzyme Mg2(+)-ATPase is modulated by the state of the lipid phase of the membrane.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Portland Press. |
| ID Code: | 75718 |
| Deposited On: | 26 Dec 2011 11:12 |
| Last Modified: | 26 Dec 2011 11:12 |
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