Elucidation of the combining site of Coccinia indica agglutinin (CIA) by thermodynamic analyses of its ligand binding

Sanadi, Ashok R. ; Ananthram, Vellareddy ; Surolia, Avadhesha (1998) Elucidation of the combining site of Coccinia indica agglutinin (CIA) by thermodynamic analyses of its ligand binding Pure and Applied Chemistry, 70 (3). pp. 677-686. ISSN 0033-4545

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Abstract

Analyses of the ligand size dependence of the fluorescence spectra of CIA together with the thermodynamic parameters for the lectin reveal that its combining site spans the tetrasaccharide chitotetraose. Moreover the fourth sugar residue of chitoligosaccharide is proximal to a highly fluorescent tryptophan.

Item Type:	Article
Source:	Copyright of this article belongs to International Union of Pure and Applied Chemistry.
ID Code:	75570
Deposited On:	24 Dec 2011 11:44
Last Modified:	18 May 2016 19:32

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