Changes in pontine unit activity with REM sleep deprivation

Mallick, B. N. ; Siegel, J. M. ; Fahringer, H. (1990) Changes in pontine unit activity with REM sleep deprivation Brain Research, 515 (1-2). pp. 94-98. ISSN 0006-8993

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Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0006-8993(90)90581-U

Abstract

Short term rapid eye movement (REM) sleep deprivation produced a decrease in waking discharge rates of presumably noradrenergic pontine 'REM sleep-off' cells and an increase in waking discharge rates of pontine 'REM sleep-on' cells. These changes can be viewed as a correlate of increased REM sleep pressure. Slowing of REM sleep-off cells in waking is hypothesized to counteract the functional effects of REM sleep loss on noradrenergic receptor sensitivity. This slowing and the resulting in norepinephrine release may contribute to the loss of vigilance seen with sleep deprivation.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Rapid Eye Movement Sleep; Pons; Norepinephrine; Locus Cerules; Reticular
ID Code:75501
Deposited On:24 Dec 2011 05:00
Last Modified:24 Dec 2011 05:00

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