Structural insight into oxybenzotriazole based coupling reagents

Srinivasa, T. K. ; Haq, W. ; Bhanumati, S. ; Velmurugan, D. ; Sharma, U. ; Jagannathan, N. R. ; Katti, S. B. (2001) Structural insight into oxybenzotriazole based coupling reagents Protein and Peptide Letters, 8 (1). pp. 39-44. ISSN 0929-8665

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Official URL: http://www.ingentaconnect.com/content/ben/ppl/2001...

Related URL: http://dx.doi.org/10.2174/0929866013409661

Abstract

Present work encompasses a detailed solution and solid phase NMR spectroscopic studies on oxybenzotriazole based coupling reagents namely HBTU (1), NBTU (2) and BOP (3). The present finding unequivocally establish that the correct structure of oxybenzotriazole based coupling reagents both in the solution and solid states are benzotriazolyl N-oxides as shown in 1a, 2a and 3a and not the uronium form as represented in the current literature.

Item Type:Article
Source:Copyright of this article belongs to Bentham Science Publishers.
Keywords:Oxybenzotriazole Based Coupling Reagents
ID Code:74327
Deposited On:12 Dec 2011 04:22
Last Modified:12 Dec 2011 04:22

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