Sudeep, A. B. ; Jadi, R. S. ; Mishra, A. C. (2009) Ganjam virus Indian Journal of Medical Research, 130 . pp. 514-519. ISSN 0019-5340
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Abstract
Ganjam virus (GANV), a member of genus Nairovirus of family Bunyavirdae is of considerable veterinary importance in India. Though, predominantly tick borne, GANV was also isolated from mosquitoes, man and sheep. Neutralizing and complement fixing antibodies to GANV have been detected in animal and human sera collected from different parts of the country. Thirty three strains of GANV have been isolated from India, mainly from Haemaphysalis ticks. The virus replicated in certain vertebrate and mosquito cell lines and found pathogenic to laboratory animals. One natural infection and five laboratoryacquired infections in men were also reported. GANV is antigenically related to Nairobi sheep disease virus (NSDV) of Africa, which is highly pathogenic for sheep and goats causing 70-90 per cent mortality among the susceptible population. Recent molecular studies have demonstrated that GANV is an Asian variant of NSDV and both these viruses are related to the dreaded Crimean Congo haemorrhagic fever (CCHF) group viruses. The versatility of the virus to replicate in different arthropod species, its ability to infect sheep, goat and man makes it an important zoonotic agent.
Item Type: | Article |
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Source: | Copyright of this article belongs to Indian Council of Medical Research. |
Keywords: | Ganjam Virus; Haemaphysalis Intermedia; Nairobi Sheep Disease; Nairovirus; Tick |
ID Code: | 73619 |
Deposited On: | 06 Dec 2011 11:03 |
Last Modified: | 18 May 2016 18:22 |
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