Singh, Neeloo ; Sundar, Shyam ; Williams, Fionnuala ; Curran, Martin D. ; Rastogi, Anil ; Agrawal, Suraksha ; Middleton, Derek (1997) Molecular typing of HLA class I and class II antigens in Indian kala-azar patients Tropical Medicine and International Health, 2 (5). pp. 468-471. ISSN 1360-2276
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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1365-...
Related URL: http://dx.doi.org/10.1111/j.1365-3156.1997.tb00169.x
Abstract
HLA has been shown to be associated with many diseases. To find out whether host genetic factors like the HLA are involved in susceptibility to kala-azar (visceral leishmaniasis) in India, we formulated an association study with genetically related controls. All samples were typed by PCR SSOP (sequence specific oligonucleotide probes) for HLA class I (A and B) and class II (DR) antigens. The test of association we used was the transmission disequilibrium test (TDT). No significant evidence for association with any of the three HLA loci was obtained.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| Keywords: | HLA; Kala-azar; India |
| ID Code: | 71534 |
| Deposited On: | 25 Nov 2011 07:01 |
| Last Modified: | 25 Nov 2011 07:01 |
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