Genetic location of rra mutation and its role in alleviation of rgl restriction

Kannan, P. ; Dharmalingam, K. (1990) Genetic location of rra mutation and its role in alleviation of rgl restriction Current Microbiology, 21 (1). pp. 1-5. ISSN 0343-8651

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Official URL: http://www.springerlink.com/content/v963kr3x645572...

Related URL: http://dx.doi.org/10.1007/BF02090092

Abstract

Restriction of glucosyl-free HMC-DNA mediated by RglB is alleviated inrecBC sbcA strains ofE scherichia coli K12. Mutation in the unlinked rra gene reverses this recBC sbcA-mediated alleviation. The map position of rra is 90.16 min on the standard map, and the rra + gene product counteracts Rgl restriction. The activation of the rra gene is controlled by the sbcA gene, and this regulation does not seem to require the involvement of other gene functions.

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