Synthesis of a new c2-symmetric molecule with dimeric hydroxyethylene isosteric moiety

Chakraborty, T. K. ; Dutta, S. (1997) Synthesis of a new c2-symmetric molecule with dimeric hydroxyethylene isosteric moiety Synthetic Communications, 27 (23). pp. 4163-4172. ISSN 0039-7911

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Official URL: http://www.tandfonline.com/doi/abs/10.1080/0039791...

Related URL: http://dx.doi.org/10.1080/00397919708005464

Abstract

As part of our studies directed toward the development of new HIV protease inhibitors, a new type of C2-symmetric molecule having a dimeric hydroxyethylene isosteric moiety is synthesised by Cu(II)-mediated dimerisation of the sodium enolate of an amino acid-derived methylketo copound.

Item Type:Article
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ID Code:69590
Deposited On:14 Nov 2011 03:51
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