Pal, Sudip ; Mitra, Kalyan ; Azmi, Sarfuddin ; Ghosh, Jimut Kanti ; Chakraborty, Tushar Kanti (2011) Towards the synthesis of sugar amino acid containing antimicrobial noncytotoxic CAP conjugates with gold nanoparticles and a mechanistic study of cell disruption Organic and Biomolecular Chemistry, 9 (13). pp. 4806-4810. ISSN 1477-0520
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Official URL: http://pubs.rsc.org/en/content/articlelanding/2011...
Related URL: http://dx.doi.org/10.1039/C1OB05338H
Abstract
Cationic antimicrobial peptides are potent inhibitors of growth of a broad spectrum of micro-organisms but often have large cytotoxic effects. We prepared some novel sugar amino acid containing cyclic cationic peptides and their Au nanoparticle attached counterparts and studied their antimicrobial activities and cytotoxic behaviour, including an investigation of the mechanism of the cytotoxicity.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Royal Society of Chemistry. |
| ID Code: | 69572 |
| Deposited On: | 14 Nov 2011 03:53 |
| Last Modified: | 14 Nov 2011 03:53 |
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