Sharma, S. K. ; Verma, U. ; Pande, J. N. ; Murugesan, K. ; Verma, K. ; Guleria, J. S. (1988) Glucocorticoid receptors in bronchoalveolar lavage fluid in sarcoidosis. A preliminary report Chest, 93 (3). pp. 577-579. ISSN 0012-3692
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Official URL: http://chestjournal.chestpubs.org/content/93/3/577...
Related URL: http://dx.doi.org/10.1378/chest.93.3.577
Abstract
Glucocorticoid receptor (GR) content was measured in bronchoalveolar lavage fluid (BALF) cells of 20 untreated patients with sarcoidosis. A significantly higher (p < 0.001) lymphocyte count and GR content of BALF cells was noted in patients with sarcoidosis as compared to normal volunteers. The GR content correlated positively with lymphocytes (%) (r = 0.6; p < 0.01) and was significantly higher (p < 0.001) in patients who showed roentgenographic improvement, physiologic improvement, and improvement in both parameters compared to those who did not show improvement. Above findings suggest that the GR content of BALF cells is increased in sarcoidosis and a major contribution to this may be made by the lymphocytes.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American College of Chest Physicians. |
| ID Code: | 69167 |
| Deposited On: | 08 Nov 2011 11:17 |
| Last Modified: | 08 Nov 2011 11:17 |
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