Chaturvedi, U. C. ; Shukla, M. I. (1981) Characterization of the suppressor factor produced in the spleen of dengue virus-infected mice Annales de l'Institut Pasteur. Immunologie, 132 (3). pp. 245-255. ISSN 0769-2625
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/076926...
Related URL: http://dx.doi.org/10.1016/0769-2625(81)90075-1
Abstract
The presence of a suppressor factor (SF) has been demonstrated in the homogenate of the spleen of dengue type 2 virus (DV)-infected mice which an adoptive intravenous (i. v.) transfer-suppressed DV-specific IgM-PFC in the spleen of recipient mice. The SF has been separated by prolonged agarose-gel electrophoresis from the DV-infected mice spleen homogenate. SF is highly potent, heat-labile, trypsin-resistant and unstable at acidic and alkaline pH. It is a low molecular wieght substance which is dialysable and is not sedimented on ultracentrifugation.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Immunoregulation; Dengue Virus; Suppressor Factor; Spleen; Mouse |
| ID Code: | 6781 |
| Deposited On: | 22 Oct 2010 06:45 |
| Last Modified: | 28 May 2011 09:25 |
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