Goulding, C. W. ; Apostol, M. ; Anderson, D. H. ; Gill, H. S. ; Smith, C. V. ; Kuo, M. R. ; Yang, J. Kuk ; Waldo, G. S. ; Suh, S. Won ; Chauhan, R. ; Kale, A. ; Bachhawat, N. ; Mande, S. C. ; Johnston, J. M. ; Lott, J. Shaun ; Baker, E. N. ; Arcus, V. L. ; Leys, D. ; McLean, K. J. ; Munro, A. W. ; Berendzen, J. ; Sharma, V. ; Park, M. S. ; Eisenberg, D. ; Sacchettini, J. ; Alber, T. ; Rupp, B. ; Jacobs, W. ; Terwilliger, T. C. (2002) The TB structural genomics consortium: providing a structural foundation for drug discovery Current Drug Targets - Infectious Disorders, 2 (2). pp. 121-141. ISSN 1568-0053
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Official URL: http://www.ingentaconnect.com/content/ben/cdtid/20...
Related URL: http://dx.doi.org/10.2174/1568005023342551
Abstract
Structural genomics, the large-scale determination of protein structures, promises to provide a broad structural foundation for drug discovery. The tuberculosis (TB) Structural Genomics Consortium is devoted to encouraging, coordinating, and facilitating the determination of structures of proteins from Mycobacterium tuberculosis and hopes to determine 400 TB protein structures over 5 years. The Consortium has determined structures of 28 proteins from TB to date. These protein structures are already providing a basis for drug discovery efforts.
Item Type: | Article |
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Source: | Copyright of this article belongs to Bentham Science Publishers. |
Keywords: | Antigen 85 Protein; Structural Genomics; Tuberculosis; Mycobacterium Tuberculosis; Mt6 Protein |
ID Code: | 67356 |
Deposited On: | 29 Oct 2011 11:15 |
Last Modified: | 29 Oct 2011 11:15 |
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