Ajjampur, Sitara Swarna Rao ; Liakath, Farzana Begum ; Kannan, Arun ; Rajendran, Priya ; Sarkar, Rajiv ; Moses, Prabhakar Devarajan ; Simon, Anna ; Agarwal, Indira ; Mathew, Ann ; O'Connor, Roberta ; Ward, Honorine ; Kang, Gagandeep (2010) Multisite study of cryptosporidiosis in children with diarrhea in India Journal of Clinical Microbiology, 48 (6). pp. 2075-2081. ISSN 0095-1137
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Official URL: http://jcm.asm.org/cgi/content/abstract/48/6/2075
Related URL: http://dx.doi.org/10.1128/JCM.02509-09
Abstract
Cryptosporidium spp., a common cause of diarrhea in children, were investigated in the first multisite study in India. Diarrheal stools from hospitalized children aged <5 years from Delhi, Trichy, and Vellore were analyzed by microscopy, PCR-restriction fragment length polymorphism (RFLP), and/or sequencing at the small-subunit (SSU) rRNA and Cpgp40/15 loci for species determination and subgenotyping, respectively. Seventy of 2,579 (2.7%) children, 75% of whom were <2 years old, had cryptosporidial diarrhea as determined by microscopy. Genotyping and subgenotyping showed that Cryptosporidium hominis was the most commonly identified species (59/67 children), and subgenotypes Ie, Ia, Ib, and Id were common in all centers. A novel C. parvum subgenotype, IIn, was identified in Vellore. Meteorological analysis revealed a higher rate of cryptosporidial positivity during hotter and drier weather in Delhi.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Society for Microbiology. |
| ID Code: | 67035 |
| Deposited On: | 28 Oct 2011 11:22 |
| Last Modified: | 28 Oct 2011 11:22 |
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