An efficient base-free N-arylation of imidazoles and amines with arylboronic acids using copper-exchanged fluorapatite

Kantam, M. Lakshmi ; Venkanna, Gopaldasu T. ; Sridhar, Chidara ; Sreedhar, Bojja ; Choudary, Boyapati M. (2006) An efficient base-free N-arylation of imidazoles and amines with arylboronic acids using copper-exchanged fluorapatite Journal of Organic Chemistry, 71 (25). pp. 9522-9524. ISSN 0022-3263

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Official URL: http://pubs.acs.org/doi/abs/10.1021/jo0614036

Related URL: http://dx.doi.org/10.1021/jo0614036

Abstract

N-Arylation of imidazoles and amines with arylboronic acids was accomplished with copper-exchanged fluorapatite (CuFAP) in methanol at room temperature. The products N-arylimidazoles and N-arylamines were isolated in good to excellent yields. A variety of arylboronic acids were converted to the corresponding N-arylimidazoles and N-arylamines, demonstrating the versatility of the reaction.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:6692
Deposited On:22 Oct 2010 06:20
Last Modified:28 May 2011 08:11

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