Gholap, Atul R. ; Venkatesan, K. ; Daniel, Thomas ; Lahoti, R. J. ; Srinivasan, K. V. (2004) Ionic liquid promoted novel and efficient one pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones at ambient temperature under ultrasound irradiation Green Chemistry, 6 (3). pp. 147-150. ISSN 1463-9262
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Official URL: http://pubs.rsc.org/en/Content/ArticleLanding/2004...
Related URL: http://dx.doi.org/10.1039/B314015F
Abstract
3,4-dihydropyrimidin-2-(1H)-ones have been synthesized in excellent yields in short reaction time at ambient temperature in the absence of any added catalyst by the reaction of aromatic or aliphatic aldehydes with ethyl acetoacetate (EAA) and urea (or thiourea) in room temperature ionic liquid (IL) under ultrasound irradiation. The evidence for the role of IL in promoting this multicomponent reaction has been given. Based on this evidence, a plausible mechanistic pathway has been postulated.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Royal Society of Chemistry. |
| ID Code: | 66584 |
| Deposited On: | 27 Oct 2011 04:17 |
| Last Modified: | 27 Oct 2011 04:17 |
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