A synthetic ditryptophan conjugate that rescues bacteria from mercury toxicity through complexation

Mondal, Sudipta ; Swaroop, Shiv ; Gurunath, Ramanathan ; Verma, Sandeep (2010) A synthetic ditryptophan conjugate that rescues bacteria from mercury toxicity through complexation Tetrahedron Letters, 51 (47). pp. 6111-6115. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2010.09.047

Abstract

The synthesis of ditryptophan-pyridine conjugates and their binding to mercury ions is described. Conjugate 3 shows an excellent ability to sequester mercury from solution and rescue bacterial growth in a concentration-dependent survival assay. It is proposed that such compounds, composed primarily of bioessential/biodegradable components, could be potentially used as sequestrating agents for the removal of Hg(II) ions in detoxification strategies.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Tryptophan Conjugate; Mercury Sequestration; Mercury Sensing; Fluorescence; Self Assembly
ID Code:66234
Deposited On:21 Oct 2011 10:05
Last Modified:21 Oct 2011 10:05

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