Prajapati, Rajneesh Kumar ; Kumar, Jitendra ; Verma, Sandeep (2010) Silver-catalyzed intramolecular cyclization of 9-propargyladeninevia N3 alkylation Chemical Communications, 46 (19). pp. 3312-3314. ISSN 1359-7345
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Official URL: http://pubs.rsc.org/en/Content/ArticleLanding/2010...
Related URL: http://dx.doi.org/10.1039/C001947J
Abstract
We report the formation of a highly unusual fused, tricyclic purine derivative via N3 alkylation of 9-propargyladenine, upon activation of the acetylenic triple bond by Ag(I) ions. The participation of silver ions in this process might offer newer design paradigms for minor groove N3 DNA alkylation, antibacterial and anticancer agents.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Royal Society of Chemistry. |
| ID Code: | 66202 |
| Deposited On: | 21 Oct 2011 10:04 |
| Last Modified: | 21 Oct 2011 10:04 |
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