Verma, Sandeep ; Srivatsan, S. G. ; Claussen, Craig A. ; Long, Eric C. (2003) DNA strand scission by a Cu(I)·adenylated polymeric template: preliminary mechanistic and recycling studies Bioorganic & Medicinal Chemistry Letters, 13 (15). pp. 2501-2504. ISSN 0960-894X
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/S0960-894X(03)00501-8
Abstract
Cleavage of a model phosphate ester and supercoiled plasmid DNA by a Cu(I)·adenylated polymer template and preliminary mechanistic investigations are reported. A novel paradigm for the design of recyclable nucleolytic reagents allowing multiple use of this catalyst is also demonstrated.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 66197 |
| Deposited On: | 21 Oct 2011 09:43 |
| Last Modified: | 21 Oct 2011 09:43 |
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