Single strands induce recA protein to unwind duplex DNA for homologous pairing

Cunningham, Richard P. ; Shibata, Takehiko ; DasGupta, Chanchal ; Radding, Charles M. (1979) Single strands induce recA protein to unwind duplex DNA for homologous pairing Nature, 281 (5728). pp. 191-195. ISSN 0028-0836

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Official URL: http://www.nature.com/nature/journal/v281/n5728/ab...

Related URL: http://dx.doi.org/10.1038/281191a0

Abstract

Single-stranded DNA, whether homologous or not, stimulates purified Escherichia coli recA protein to unwind duplex DNA. This helps to explain how recA promotes a search for homology in genetic recombination. As oligodeoxynucleotides also stimulate unwinding, a common mechanism may relate the function of recA protein in recombination to other functions (SOS) induced by oligonucleotides.

Item Type:Article
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ID Code:65835
Deposited On:19 Oct 2011 09:07
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