Kotha, Sambasivarao ; Deb, Ashoke Chandra ; Kumar, Ramanatham Vinod (2005) Spiro-annulation of barbituric acid derivatives and its analogs by ring-closing metathesis reaction Bioorganic & Medicinal Chemistry Letters, 15 (4). pp. 1039-1043. ISSN 0960-894X
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.bmcl.2004.12.034
Abstract
Barbituric acid 1 and related β-dicarbonyl compounds were dialkenylated under the phase-transfer catalyst [e.g., benzyltriethylammonium chloride (BTEAC)] conditions to generate the diallylated products. These diallylated products were subjected to the ring-closing metathesis (RCM) reaction to deliver the corresponding spiro-annulated derivatives.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | RCM; Spirocycles; Barbituric Acid; 1,3-Dicarbonyl Compound |
| ID Code: | 65160 |
| Deposited On: | 15 Oct 2011 11:42 |
| Last Modified: | 15 Oct 2011 11:42 |
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