Adam, Waldemar ; Cadet, Jean ; Dall'Acqua, Francesco ; Epe, Bernd ; Ramaiah, Danaboyina ; Saha-Möller, Chantu R. (1995) Photosensitized formation of 8-hydroxy-2'-deoxyguanosine in salmon testes DNA by furocoumarin hydroperoxides: a novel, intercalating "photo-fenton" reagent for oxidative DNA damage Angewandte Chemie International Edition, 34 (1). pp. 107-110. ISSN 1433-7851
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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/anie.19...
Related URL: http://dx.doi.org/10.1002/anie.199501071
Abstract
Furocoumarin hydroperoxides such as 1 are novel photochemical sources of hydroxyl radicals; in salmon testes DNA they form the mutagenic oxidation product 8-hydroxy-2'-deoxyguanosine 2 in up to 1.8% yield on UVA irradiation (λ = 350 nm).
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| Keywords: | DNA Oxidation; Furocoumarins; Hydroperoxides; 8-hydroxy-2'-deoxyguanosine; Hydroxyl Radicals |
| ID Code: | 63607 |
| Deposited On: | 29 Sep 2011 03:59 |
| Last Modified: | 29 Sep 2011 03:59 |
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