Highly efficient synthesis of 3-alkyl/aryl-4-aryl-1,2,3,4-tetrahydroisoquinolines from N,N-dibenzylaminols

Chandrasekhar, S. ; Ramakrishna Reddy, N. ; Venkat Reddy, M. ; Jagannadh, B. ; Nagaraju, A. ; Ravi Sankar, A. ; Kunwar, A. C. (2002) Highly efficient synthesis of 3-alkyl/aryl-4-aryl-1,2,3,4-tetrahydroisoquinolines from N,N-dibenzylaminols Tetrahedron Letters, 43 (10). pp. 1885-1888. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(02)00130-2

Abstract

Substituted tetrahydroisoquinolines are synthesized in optically pure form using a Grignard reaction of N,N-dibenzyl aminol and Friedel-Crafts cyclization as the key steps.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Substituted Isoquinolines; Friedel-crafts Cyclization; N,N-dibenzyl Aminol; AlCl3
ID Code:63494
Deposited On:29 Sep 2011 04:17
Last Modified:29 Sep 2011 04:17

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