Safe and convenient reduction of Δ2-isoxazolines with PMHS-Pd(OH)2/C

Chandrasekhar, S. ; Nagendra Babu, B. ; Ahmed, Moinuddin ; Venkat Reddy, M. ; Srihari, P. ; Jagadeesh, B. ; Prabhakar, A. (2004) Safe and convenient reduction of Δ2-isoxazolines with PMHS-Pd(OH)2/C Synlett, 2004 (7). pp. 1303-1305. ISSN 0936-5214

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Official URL: https://www.thieme-connect.com/ejournals/abstract/...

Related URL: http://dx.doi.org/10.1055/s-2004-822917

Abstract

A practical and safe reduction methodology for the conversion of Δ2-isoxazolines to 1,3-aminols is developed using polymethylhydrosiloxane-Pd(OH)2/C. In presence of (Boc)2O, the isoxazoline was converted into N-Boc protected 1,3-aminol in a one-pot procedure.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:Reduction; Polymethylhydrosiloxane; Pd(OH)2/C; Isoxazolines
ID Code:63250
Deposited On:28 Sep 2011 03:51
Last Modified:28 Sep 2011 03:51

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