A chiron approach to (−)-tetrahydrolipstatin

Yadav, J. S. ; Vishweshwar Rao, K. ; Prasad, A. R. (2006) A chiron approach to (−)-tetrahydrolipstatin Synthesis, 2006 (22). pp. 3888-3894. ISSN 0039-7881

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Official URL: https://www.thieme-connect.com/ejournals/abstract/...

Related URL: http://dx.doi.org/10.1055/s-2006-950325

Abstract

An efficient chiron approach to the total synthesis of (−)-tetrahydrolipstatin is described. The main features of the synthetic strategy, which starts from tri-O-acetyl-D-glucal, are copper-mediated- C-C bond formation, Frater alkylation, and Barton-McCombie- deoxygenation.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:(−)-tetrahydrolipstatin; Anti-obesity; Tri-O-acetyl-D-glucal; Frater Alkylation
ID Code:63218
Deposited On:28 Sep 2011 03:27
Last Modified:28 Sep 2011 03:27

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