Yadav, J. S. ; Niranjan Kumar, N. ; Prasad, A. R. (2007) Stereoselective synthesis of a key intermediate of (-)-apicularen A Synthesis, 2007 (8). pp. 1175-1178. ISSN 0039-7881
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Official URL: http://www.thieme-connect.com/ejournals/abstract/s...
Related URL: http://dx.doi.org/10.1055/s-2007-965979
Abstract
Progress towards the stereoselective formal synthesis of (-)-apicularen A is described. The convergent approach involves the assembly of aliphatic and aromatic fragments via Grubbs's cross metathesis. Other key reactions in the strategy include Sharpless asymmetric epoxidation, Evans's protocol for the generation of syn 1,3-diol systems and stereoselective reduction.
Item Type: | Article |
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Source: | Copyright of this article belongs to Thieme Medical Publishers. |
Keywords: | Apicularen A; Antitumor; Grubbs's Cross Metathesis; Evans's Protocol |
ID Code: | 63102 |
Deposited On: | 28 Sep 2011 03:28 |
Last Modified: | 28 Sep 2011 03:28 |
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