Yadav, J. S. ; Naga Lakshmi, P. ; Harshavardhan, S. J. ; Subba Reddy, B. V. (2007) First stereoselective total synthesis of ophiocerins B and C Synlett, 2007 (12). pp. 1945-1947. ISSN 0936-5214
Full text not available from this repository.
Official URL: https://www.thieme-connect.com/ejournals/abstract/...
Related URL: http://dx.doi.org/10.1055/s-2007-982579
Abstract
An elegant synthesis of ophiocerins B and C is accomplished for the first time with 3R,4R,6R and 3S,4S,6R-configuration. Of these three stereogenic centers, the C-3/C-4 vic-diol was created by Sharpless asymmetric dihydroxylation, while the C-6 stereocenter was achieved from known chiral epoxide. The synthesis of ophiocerins B and C defined the absolute stereochemistry of these natural products.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Thieme Medical Publishers. |
| Keywords: | Sharpless Asymmetric Dihydroxylation; Ophiocerin; Tetrahydropyran Derivative |
| ID Code: | 63071 |
| Deposited On: | 28 Sep 2011 03:28 |
| Last Modified: | 28 Sep 2011 03:28 |
Repository Staff Only: item control page
