Stereoselective synthesis of the macrocyclic core of (-)-salicylihalamides A and B

Yadav, J. S. ; Sundar Ram Reddy, P. (2007) Stereoselective synthesis of the macrocyclic core of (-)-salicylihalamides A and B Synthesis, 2007 (7). pp. 1070-1076. ISSN 0039-7881

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Official URL: http://www.thieme-connect.com/ejournals/abstract/s...

Related URL: http://dx.doi.org/10.1055/s-2007-965970

Abstract

Stereoselective synthesis of the macrocyclic core of salicylihalamides A and B is described. The synthetic strategy features stereoselective iodolactonization, Sharpless asymmetric epoxidation, Mitsunobu esterification, and ring-closing metathesis.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:Salicylihalamide; Cytotoxicity; Sharpless Epoxidation; Metathesis
ID Code:62951
Deposited On:24 Sep 2011 04:53
Last Modified:24 Sep 2011 04:53

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