Yadav, J. S. ; Praveen Kumar, S. ; Kondaji, G. ; Srinivasa Rao, R. ; Nagaiah, K. (2004) A novel L-proline catalyzed Biginelli reaction: One-pot synthesis of 3, 4-dihydropyrimidin-2 (1H)-ones under solvent-free conditions Chemistry Letters, 33 (9). pp. 1168-1169. ISSN 0366-7022
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Official URL: http://www.jstage.jst.go.jp/article/cl/33/9/33_116...
Related URL: http://dx.doi.org/10.1246/cl.2004.1168
Abstract
A Novel efficient and simple synthetic protocol for the Biginelli reaction has been developed for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones in a one-pot three-component condensation of aldehydes, β-dicarbonyl compounds, and urea or thio-urea by using 10 mol % L-proline as the catalyst under solvent free condition.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Chemical Society of Japan. |
| ID Code: | 62870 |
| Deposited On: | 24 Sep 2011 04:47 |
| Last Modified: | 24 Sep 2011 04:47 |
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