Iodotrimethylsilane-mediated cross-aldol condensation: a facile synthesis of α,α'-bis (substituted benzylidene) cycloalkanones

Sabitha, Gowravaram ; Kiran Kumar Reddy, G. S. ; Bhaska Reddy, K. ; Yadav, J. S. (2004) Iodotrimethylsilane-mediated cross-aldol condensation: a facile synthesis of α,α'-bis (substituted benzylidene) cycloalkanones Synthesis, 2004 (2). 0263-0266. ISSN 0039-7881

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Official URL: http://www.thieme-connect.com/ejournals/abstract/s...

Related URL: http://dx.doi.org/10.1055/s-2004-815920

Abstract

A facile and efficient method for the preparation of α,α'-bis(substituted benzylidene)cycloalkanones is described for the first time using iodotrimethylsilane generated in situ from chlorotrimethylsilane and sodium iodide in acetonitrile. The reaction proceeds rapidly at room temperature, giving high yields of products.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:Iodotrimethylsilane; Cross-aldol Condensation; Ambient Temperature; Cyclic Ketones
ID Code:62847
Deposited On:24 Sep 2011 04:47
Last Modified:24 Sep 2011 04:47

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