One-pot synthesis of dihydropyrimidinones using iodotrimethylsilane. Facile and new improved protocol for the biginelli reaction at room temperature

Sabitha, Gowravaram ; Kiran Kumar Reddy, G. S. ; Srinivas Reddy, Ch. ; Yadav, J. S. (2003) One-pot synthesis of dihydropyrimidinones using iodotrimethylsilane. Facile and new improved protocol for the biginelli reaction at room temperature Synlett, 2003 (6). 0858-0860. ISSN 0936-5214

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Official URL: https://www.thieme-connect.com/ejournals/abstract/...

Related URL: http://dx.doi.org/10.1055/s-2003-38734

Abstract

A novel one pot condensation of an aldehyde, β-ketoester and urea has been performed using TMSI in acetonitrile for the first time at room temperature affording dihydropyrimidinones in excellent yields.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:Biginelli Reaction; Dihydropyrimidinones; Iodotrimethyl Silane; One-pot Condensation; Room Temperature
ID Code:62761
Deposited On:24 Sep 2011 04:42
Last Modified:24 Sep 2011 04:42

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