Yadav, J. S. ; Reddy, B. V. S. ; Naidu, Jaishri J. ; Sadashiv, K. (2004) NbCl5-catalyzed rapid and efficient synthesis of 3, 4-dihydropyrimidinones under ambient conditions Chemistry Letters, 33 (7). pp. 926-927. ISSN 0366-7022
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Official URL: http://www.jstage.jst.go.jp/article/cl/33/7/33_926...
Related URL: http://dx.doi.org/10.1246/cl.2004.926
Abstract
Three-component condensation of an aldehyde, 1,3-dicarbonyl compound and urea or thiourea proceeds smoothly at room temperature in the presence of 5 mol % of NbCl5 under extremely mild conditions to afford the corresponding 3,4-dihydropyrimidines in high to quantitative yields. This method is very useful for the synthesis of a wide range of dipyrimidinones at room temperature from aromatic, heterocyclic, and aliphatic aldehydes.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Chemical Society of Japan. |
| ID Code: | 62759 |
| Deposited On: | 24 Sep 2011 04:48 |
| Last Modified: | 24 Sep 2011 04:48 |
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