Stereoselective total synthesis of bistramide A

Yadav, J. S. ; Chetia, Lakshindra (2007) Stereoselective total synthesis of bistramide A Organic Letters, 9 (22). pp. 4587-4589. ISSN 1523-7060

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Official URL: http://pubs.acs.org/doi/abs/10.1021/ol702095n

Related URL: http://dx.doi.org/10.1021/ol702095n

Abstract

A highly stereoselective and convergent total synthesis of bistramide A is described. The salient feature of this synthesis is the construction of the spiroketal subunit by hydrolysis of dialkylated tosylmethyl isocyanide derivative derived via alkylation of TosMIC with suitably substituted halohydrin derivatives.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:62741
Deposited On:24 Sep 2011 04:54
Last Modified:24 Sep 2011 04:54

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