Samarium triflate-catalyzed biginelli condensation: An improved method for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones

Venkat Narsaiah, A. ; Ramesh Reddy, A. ; Yadav, J. S. (2011) Samarium triflate-catalyzed biginelli condensation: An improved method for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones Synthetic Communications, 41 (18). pp. 2794-2799. ISSN 0039-7911

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Official URL: http://www.tandfonline.com/doi/abs/10.1080/0039791...

Related URL: http://dx.doi.org/10.1080/00397911.2010.515355

Abstract

A simple and efficient method for multicomponant synthesis of 3,4-dihydropyrimidinones has been reported. All the reactions were carried out using samarium triflate as catalyst (10 mol%) at acetonitrile reflux. This procedure is applicable to a variety of substrates such as aliphatic, aromatic, and heterocyclic aldehydes.

Item Type:Article
Source:Copyright of this article belongs to Taylor and Francis Group.
Keywords:Aldehydes; Biginelli Reaction; β-ketoester; Sm(oTf)3; Urea
ID Code:62715
Deposited On:24 Sep 2011 05:02
Last Modified:24 Sep 2011 05:02

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