Stereoselective synthesis of (−)-bulgecinine hydrochloride and its C-2 epimer from L-ascorbic acid

Chandrasekhara, Srivari ; Chandrashekar, Gudise ; Vijeendera, Kandi ; Dattatreya Sarma, Ganti (2006) Stereoselective synthesis of (−)-bulgecinine hydrochloride and its C-2 epimer from L-ascorbic acid Tetrahedron: Asymmetry, 17 (20). pp. 2864-2869. ISSN 0957-4166

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetasy.2006.10.033

Abstract

An efficient strategy for the stereocontrolled synthesis of (−)-bulgecinine hydrochloride 1 was accomplished by utilizing a Wittig Horner olefination, stereoselective reduction of the double bond and intramolecular N-alkylation to furnish the target.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:62380
Deposited On:22 Sep 2011 03:30
Last Modified:22 Sep 2011 03:30

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