Chandrasekhar, S. ; Parimala, Ganney ; Tiwari, Bhoopendra ; Narsihmulu, Ch. ; Dattatreya Sarma, G. (2007) Asymmetric synthesis of a protected dihydroxypiperazic acid derivative Synthesis, 2007 (11). pp. 1677-1682. ISSN 0039-7881
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Official URL: https://www.thieme-connect.com/ejournals/abstract/...
Related URL: http://dx.doi.org/10.1055/s-2007-966062
Abstract
A short and flexible route for the synthesis of 1,2-diisopropyl-3-methyl-(3S,4R,5R)-4,5-dihydroxy hexahydro-1,2,3-pyrid-azinetricarboxylate, from readily available acrolein, is described. This approach involves an asymmetric α-hydrazination, dihydroxylation and intramolecular cyclisation as key steps.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Thieme Medical Publishers. |
| Keywords: | Piperazic Acid; L-Proline; α-Hydrazination; Dihydroxylation; Intramolecular Cyclisation |
| ID Code: | 62377 |
| Deposited On: | 22 Sep 2011 03:30 |
| Last Modified: | 22 Sep 2011 03:30 |
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