Proline-threonine dipeptide as an organocatalyst for the direct asymmetric aldol reaction

Chandrasekhar, Srivari ; Johny, Kancharla ; Raji Reddy, Chada (2009) Proline-threonine dipeptide as an organocatalyst for the direct asymmetric aldol reaction Tetrahedron: Asymmetry, 20 (15). pp. 1742-1745. ISSN 0957-4166

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetasy.2009.06.018

Abstract

A new proline-threonine (H-Pro-Thr-OH) dipeptide has been demonstrated as an efficient organocatalyst for a direct asymmetric aldol reaction. It was found that this new peptide-based catalyst efficiently catalyzed the reaction between an aldehyde and acetone to provide β-hydroxy ketones in good yields with good enantioselectivities.

Item Type:Article
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ID Code:62342
Deposited On:22 Sep 2011 03:36
Last Modified:22 Sep 2011 03:36

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