Synthesis of readily accessible triazole-linked dimer deoxynucleoside phosphoramidite for solid-phase oligonucleotide synthesis

Chandrasekhar, Srivari ; Srihari, Pabbaraja ; Nagesh, Chidalla ; Kiranmai, Nayani ; Nagesh, Narayana ; Mohammed Idris, M. (2010) Synthesis of readily accessible triazole-linked dimer deoxynucleoside phosphoramidite for solid-phase oligonucleotide synthesis Synthesis, 2010 (21). pp. 3710-3714. ISSN 0039-7881

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Official URL: https://www.thieme-connect.com/ejournals/abstract/...

Related URL: http://dx.doi.org/10.1055/s-0030-1258243

Abstract

A concise preparation of triazole-linked deoxynucleoside phosphoramidite for its direct use in solid-phase oligonucleo-tide synthesis is reported. This dimer has successfully been utilized in solid-phase synthesis to make the 10- and 12-mer oligomers.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:Nucleotides; Triazole; Click; Oligomer; Solid-phase Synthesis
ID Code:62329
Deposited On:22 Sep 2011 03:37
Last Modified:22 Sep 2011 03:37

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